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Have a gastrointestinal condition like gastritis or Crohns disease
Maintenance dosing is highly individualized, with semaglutide maintenance typically ranging from 0.5 to 1.7 mg weekly (some patients remain stable on 0.25 mg), and tirzepatide maintenance commonly ranging from 5 to 7.5 mg weekly, while a minority stabilize at 2.5 mg
Semaglutide produces greater weight loss as monotherapy (15-17% vs 11.8%), but the two peptides can be combined for additive effects
Ozempic mimics the hormone GLP-1 (glucagon-like peptide-1), while Mounjaro mimics both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide or gastric inhibitory polypeptide)
This step-wise approach allows your body to gradually adjust to the medication, reducing the severity of initial side effects