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Glucose levels in 4 h-fasted animals were reduced in MEDI4166-treated mice in a dose-dependent manner with the mid and high doses significantly delaying the progression of diabetes (Fig

Abstract Background Glucagon-like peptide-1 receptor agonists (GLP-1RA) have cardiovascular benefits in type 2 diabetes, but none of the cardiovascular trials studied atrial fibrillation/atrial flutter (AF) as a primary endpoint

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