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METHODS Godex prevented diet-induced obesity After 8 weeks, there was a 64% increase in body weight in the HFD group compared to the ND group
Limitations include relatively short treatment periods (6 weeks per arm), potential carryover effects despite washout, modest sample size limiting power for subgroup analyses and exclusion of newer agents (e.g., tapentadol) and long-term safety outcomes, which may restrict applicability to broader clinical practice
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While most people tolerate both well, some may experience mild digestive upset when first starting probiotics
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