There is growing evidence indicating that GLP-1 activates both Gq and Gs signalling pathways, whereas the effects of GIP and GCG are mediated exclusively through Gs [13]
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In posterior segments of the gut (e.g., the cecum and proximal large intestine), gut microbes directly cleave the CN bond of carnitine to release TMA, which subsequently enters the liver through the portal circulation, is converted to TMAO by hepatic flavin monooxygenases (FMOs) [242, 243], and eventually enters the blood circulation [244]
5.00 7.00Price range: 5.00 through 7.00 For laboratory research use only
Massi L, Elezgarai I, Puente N, Reguero L, Grandes P, Manzoni OJ, et al
I personally go for the 500mg dose because that is what I usually use and the difference between the two is 20p or 24p per serving so you get double dose for only 4p more per serving so makes economic sense too