Mol Psychiatry 26:54815503
MAUD-T2D trial: Patients with T2D and markers of more severe AUD, comparing newer GLP-1 RAs to FDA-approved medications for AUD (MAUD: acamprosate, disulfiram, or naltrexone)
PlexusDx delivers pharmaceutical-grade compounded semaglutide injections through licensed 503A pharmacies, making this proven therapy accessible without insurance
A review of pivotal clinical trials for semaglutide (STEP, SUSTAIN), dulaglutide (REWIND), liraglutide (LEADER), and tirzepatide (SURPASS, SURMOUNT) does not identify muscle cramps as occurring at significantly higher rates compared to placebo groups
Potential adverse side effects over time could impact the usability or medical viability of the drugs
The best course of action is to ease into the calorie deficit and adjust as needed to create a lasting lifestyle modification