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Researchers compared people prescribed GLP-1 receptor agonists with those taking other diabetes drugs or no such medications
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doi:10.1016/j.cmet.2018.03.001 25
The exact cause is not fully understood, but it may relate to the bodys response to the drug or dehydration
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Tirzepatide# Tirzepatide is a 39-amino acid peptide with a C20 fatty diacid side chain that activates two receptors: GIP receptor : Tirzepatide shows approximately 5-fold selectivity for GIP over GLP-1 receptors, representing a GIP-dominant dual agonist GLP-1 receptor : Provides complementary glucose-lowering and appetite-suppressing effects The GIP receptor engagement is a key differentiator from pure GLP-1 agonists like semaglutide
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