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A dysfunction in System Xc- results in reduced cysteine availability, which limits GSH synthesis, weakens antioxidant defenses, and increases susceptibility to lipid peroxidation, thereby accelerating ferroptosis (67)
The practical reality involves individual use occurring under this research designation, though such use technically falls outside intended purposes
Individuals with active cancer, recent cancer history, or strong family history of aggressive cancers should avoid BPC-157 as a precautionary measure
Kelly and Pearce, 2020
[9] Its approved status is also reflected in the ChEMBL registry at max phase 4
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