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269 In EGFR-mutant NSCLC, AXL activation by GAS6 stabilizes the E3 ligase RAD18 via ubiquitin-like modification, promoting monoubiquitination of PCNA and facilitating error-prone translesion DNA synthesis, thus accelerating mutagenesis and resistance
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Comprehensive Detoxification: Essential for the body's natural detox pathways, particularly in the liver, aiding in the efficient elimination of toxins and maintaining cellular purity
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