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Community-reported (anecdotal): headache, brain fog or mental fatigue, irritability, anxiety, nausea or other GI upset, appetite and sleep changes, blood-pressure changes, and skin reactions with transdermal-DMSO use

Perrelli M-G, Pagliaro P, Penna C

Conditions where the bone marrow overproduces blood cells, including polycythemia vera, chronic myeloid leukemia (CML), and hypereosinophilic syndrome , can cause elevated B12 levels

OPJS University, Rajasthan, India

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The 81.2% reduction in MRI-PDFF liver fat fraction seen in the phase 2 subset is the largest hepatic fat reduction reported for any single injection-based agent in a published randomized controlled trial as of early 2025 [1, 6]