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J Chem Educ 95(5):864871

These maleimide functional groups play dual roles, that permitting a Toll-like receptor 2 binding peptide conjugation in order to improve cancer cell specific delivery, in the other hand, once in cytosol, maleimide efficiency improve oridonins redox imbalance promoting ability by simultaneous GSH depletion

Moreover, ferroptosis is increasingly recognized as an important driver of disease pathogenesis, including but not limited to cancer, degenerative diseases, ischemic injury, and infections [25]

K.Au EongJ

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