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Description

In our study, FOXO4-DRI selectively induced apoptosis in senescent keloid fibroblasts by promoting the relocation of p53-pS15 from the nucleus to the cytoplasm, exhibiting similar clearance efficiency to that in normal skin fibroblasts

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The decision to move Meldonium from the Monitoring program to the Prohibited list was made because of evidence of its use by athletes with the intention of enhancing performance (WADA 2016 Prohibited List, 16 September 2015), rather than robust scientific evidence demonstrating actual performance enhancement

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One small randomized controlled trial demonstrated that intravenous followed by oral thiamin therapy improved left ventricular ejection fraction in 30 CHF patients

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