the discovery and development of liraglutide and semaglutide Designing GLP-1 delivery: structural perspectives formulation approaches for optimized therapy Semaglutide from Bench to Bedside:

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doi: 10.3389/fphar.2020.00967 Received 17 March 2020 Accepted 15 June 2020 Published 30 June 2020 Volume 11 - 2020 Edited by Keizo Kanasaki, Shimane University, Japan Reviewed by Shinji Kume, Shiga University of Medical Science, Japan

HR, hazard ratio

GLP-1 medications may be appropriate for adults with: BMI 30 kg/m BMI 27 kg/m with obesity-related conditions such as diabetes, hypertension, sleep apnea, or fatty liver disease Difficulty losing weight despite lifestyle changes Treatment suitability should always be determined by an endocrinologist after a comprehensive evaluation

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Many redirect their spending toward fresh produce or protein-rich foods, reflecting both physical and psychological shifts in their approach to eating