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I tried increasing the frequency of SI from 2 weekly to 1 weekly and the flushing got much worse - so I think this is the likely culprit

DKD, diabetic kidney disease

It is produced mainly by the liver and is involved in multiple biological processes such as When glutathione levels decrease, the skin becomes dull, pigmented, uneven, and more prone to oxidative damage

Healthy detox pathways are also linked to Gut Health, which plays a growing role in skin balance and inflammation control

The clinical effects appear to be influenced by several key factors, including patient characteristics (age, gender, ethnicity), concurrent medical conditions (particularly diabetes and obesity), and treatment parameters (drug type, dosage, duration) [9, 10]

the Injury Recovery Protocol is the five-compound version with the TB-500 bolus (12.5 mg, 2-3x per week) and NAD+ that the cocktail cant carry