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Pharmacodynamics: Tesamorelin is a stabilized analog of growth hormonereleasing hormone (GHRH) that stimulates the anterior pituitary to increase endogenous growth hormone secretion, leading to elevated IGF-1 levels and downstream metabolic effects

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It non-selectively activates melanocortin receptors (MC1, MC3, MC4, MC5) and is involved in the regulation of various physiological processes including pigmentation, energy balance, sexual function, and inflammatory responses

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Biomedicine & Pharmacotherapy, 142 , 112024