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Instead of competing solely on price, pharmaceutical companies are redesigning successful biologics to deliver: Improved efficacy Longer half-life Better safety profiles Reduced immunogenicity Enhanced patient convenience The economics are compelling: Biosimilars compete in a discount-driven market with limited exclusivity
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To test if the increased mitochondrial OXPHOS is caused by an increased mitochondrial biogenesis, we performed transmission electron microscopy (TEM) in NIT-1 cells, which is an immortalized NOD -cell line 55 , transfected with either empty or MOTS-c vector
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