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Their work, published in peer-reviewed journals, demonstrated that blocking this enzyme could produce significant changes in body composition without affecting food intake

True allergy to hydroxocobalamin is rare but real, so a brief history matters

Inhibition of NNMT by 5-Amino-1MQ and Its Effects on Fat Metabolism. Cellular Metabolism , 33(7), 1345-1358

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Kraus et al

Based on current understanding, 5-amino-1MQ shouldn't interfere with the weight loss effects of Tirzepatide