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At the same time, IR780 generated large amounts of ROS in response to US treatment, disrupting normal mitochondrial function and inducing ICD (42)
Li et al., to have a better understanding of the effect of NAC on MDA in heat stress-induced intestinal injury, designed a study consisting of in vivo (NAC pretreated -C57BL/6 mice kept in a pre-warmed incubator until reaching a rectal core temperature of 42 C) and in vitro (using IEC-6 cells incubated for 2 h at 43 C to induce heat stress and pretreated with NAC) experiments [49]
6,7 Drugs belonging to this class include liraglutide, semaglutide, and dulaglutide, among others
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For in vitro experiments, intra-experimental replicate mean was treated as a single replicate
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