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Circadian variation in gastric emptying of meals in humans

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Ethics statement The studies involving humans were approved by the University of Helsinki, Faculty of Medicine

The most commonly reported adverse effects are gastrointestinal in nature and include: Nausea (particularly during dose escalation) Vomiting Diarrhoea Constipation Decreased appetite These effects are generally dose-dependent and tend to be most pronounced during the initial weeks of treatment when the dose is being gradually increased

In the standard NHS setting, a "normal" TSH result is often anything within a very broad range

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