First, it interacts with the hunger centers in the brain to reduce appetite and suppress cravings
Losing weight can help regulate these hormones, which may lead to more predictable cycles, especially for people with obesity or PCOS
Eventually, semaglutide was developed and branded as Ozempic, which could be injected just once a week
Dietary modifications can substantially reduce symptoms: Consume smaller, more frequent meals rather than large portions Avoid high-fat, greasy, or heavily spiced foods that delay gastric emptying further Eat slowly and chew food thoroughly Stay well-hydrated, taking small sips of water throughout the day Avoid lying down immediately after eating (remain upright for 23 hours post-meal) Identify and avoid personal trigger foods that worsen nausea Timing of medication administration may also help
Common (Usually Mild to Moderate) These often improve as the body adjusts: Nausea Reduced appetite Feeling full quickly Bloating or indigestion Constipation or diarrhoea Mild fatigue Less Common Side Effects Vomiting Acid reflux or heartburn Dizziness Headaches Changes in bowel habits These may occur if dose escalation is too fast or dietary intake is not adjusted
It is recognised as one of the first growth hormone-releasing peptide receptor agonists designed with high selectivity for growth hormone stimulation