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Further modification of clofazimine to improve its pharmacokinetics and randomized clinical trials to ascertain its clinical performance are warranted
It carries four substitutions, notably D-Ala at position 2, studied in vitro for increased resistance to dipeptidyl-peptidase-IV (DPP-IV) cleavage
doi: 10.3389/fnagi.2022.976316 163 WangS.LvD.JiangS.JiangJ.LiangM.HouF.et al
Petrov, M
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