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However, as companies pursue more convenient oral formulations, the uncomfortable truth is that injectable drugs maintain market dominance for reasons rooted in basic pharmacology

But understanding why this happens with semaglutide, tirzepatide and other GLP-1 drugs could be crucial to understanding their longer-term health consequences and how best to prescribe them in future

The GLP-1 Effect: Market Penetration In the UK, 4.2 million adultsnearly 1 in 10had recently used a GLP-1 medication or expressed interest in doing so as of early 2025 Two in five overweight Britons (38%) express interest in using GLP-1s for weight loss when informed about the drugs Across Europe, the GLP-1 market is valued at 9.62 billion in 2025, with robust growth expected due to rising obesity and diabetes rates, improved access, and strong healthcare infrastructure in markets like Germany, France, and the UK Social acceptance is rising, and insurance coverage is likely to expand, further accelerating adoption

These results highlight the potential of oral GLP1 options to expand patient access and accelerate adoption within the market

10.1038/s41598-019-51880-9 Sci