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Clinical Trials: Impact of B12 Supplementation on Metabolites Below are four graphs showing the response to B12 supplementation of serum B12, holotranscobalamin, MMA, and homocysteine: Eight trials of predominantly older adults with at least mild deficiency (Dangour, 2015
Research Characteristics: BPC-157: Investigated for activity related to angiogenesis and inflammatory signaling pathways
Others may need GP-led investigation, blood tests or long-term treatment depending on the cause of deficiency
But long-term safety data is lacking
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