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This pharmacological effect, while beneficial for glycemic control and weight loss, may exacerbate gastrointestinal symptoms in individuals with active or poorly controlled celiac disease
Still, in most cases, they are a skin-level responsenot a sign of harm or failure
The most common side effects noted to date have been gastrointestinal, specifically nausea and constipation
Some nations maintain lists of controlled or prohibited substances that may include certain weight loss medications
The primary actions of secretin include induction of bile secretion from the gallbladder into the duodenum, enhanced secretion of bicarbonate and H 2 O into the duodenum from the pancreas, and increased gastric pepsin secretion
The fact that real-world results come within a few percentage points of trial data speaks to tirzepatide's robust efficacy even under imperfect conditions
