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These are the glue that keeps the gut lining and vascular barriers intact, which is why it is often cited in discussions regarding leaky gut and systemic inflammation
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The mechanism appears to involve increased serotonin synthesis in substantia nigra, a regional pattern unlike any existing antidepressant drug
Dehydration represents an important factor, as GLP-1 medications can cause nausea, vomiting, and diarrhea, particularly during dose escalation, leading to volume depletion
Current clinical evidence suggests associations with reductions in body weight and AHI, along with improved glycemic control, although these benefits appear largely mediated by metabolic effects
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