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This frequency provides a "use it or lose it" signal to the muscular system
588,168 adults with type 2 diabetes: 139,546 started a GLP-1 drug 448,622 started an SGLT2 inhibitor Followed for up to 3 yearsAt 3 years, NAION was more frequent among people who started GLP-1 drugs: GLP-1 drugs: 39.1 cases per 10,000 persons SGLT2 inhibitors: 29.3 cases per 10,000 persons That works out to 6 to 10 extra cases per 10,000
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Fear of Long-term Use There can be concerns about the long-term use of any medication, especially if its long-term effects arent fully understood
A report published in Health Affairs estimated the cost of oral medication rose by 9% between 2008 and 2016, whereas injectable drugs rose by 15% in the same time frame
Reconstitution (if applicable) Some compounded GLP-1 medications arrive as lyophilized powder that requires reconstitution with bacteriostatic water
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