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It's prescribed alongside changes to diet and activity, as part of a medically supervised plan not on its own, and not as a shortcut

J Gastroenterol Hepatol 32(9):16401648 Zhang HQ et al (2009) Therapeutic effects of Clostridium butyricum on experimental colitis induced by oxazolone in rats

Pay attention to side effects, especially nausea, dehydration, and gallbladder symptoms, and report them to your prescriber early rather than waiting

The SURPASS-2 head-to-head trial provides the cleanest comparison, since both groups were studied under identical conditions

You've also said and I think this is something else we've learned over that time that obesity is not one thing

Most patients regain approximately two-thirds of lost weight within one year of stopping GLP-1 therapy, based on the STEP 4 trial withdrawal data