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Table 2 The table illustrates the molecular structures of seven pharmacologically active phytochemicals identified in TCMs commonly applied in DKD management: Cordycepin ( Cordyceps sinensis ), Astragaloside IV ( Astragalus membranaceus ), Puerarin ( Pueraria lobata ), Gypenoside XVII ( Gynostemma pentaphyllum ), Triptolide ( Tripterygium wilfordii ), Notoginsenoside R1 ( Panax notoginseng ), and Osthole ( Cnidium monnieri )

Since the first IGF-1 radioimmunoassay in 1977, many methods for detecting IGF-1 have been introduced, including radioimmunoassay, ELISA, immuno-chemoluminescence, and mass spectrometry-based assays

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Similarly, studies in apple and melon have integrated QTLs with expression QTL (eQTL) data to associate loci with polyphenolic content and aroma profiles, demonstrating that rapid QTL discovery and DNA marker development is feasible even in heterozygous polyploid species (Yamakawa et al

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