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PMID: 4144403
doi: 10.1152/ajpheart.00763.2001 144 NguyenK.ChauV
International journal of cell biology
Work from our and other groups showed that LAC also modulates acetylation of NF-B/p65 subunit, which potentiates the transcriptional activity of NF-B member to increase transcription of the Grm2 gene encoding for the mGlu2 receptor in hippocampus and prefrontal cortex of FSL rats [30, 36]
Other reported side effects include flushing (20%), injection site reactions (13%), and headache (11%)
Its use in the UK would therefore constitute off-label prescribing at best, or unlicensed importation in most practical scenarios
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