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Acknowledgements This research was supported by US Public Health Service grants R01HL088256, R01AR070837, P01HL152958, and R01DK110162 to S.D.C

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Nevertheless, larger independent single-cell or spatially resolved cohorts will be required to validate PT-specific and other cell-type-specific metabolic remodeling in TCMR

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3), Geldenhuys showed a ~ 2-fold increase in the delivery of coumarin-6 to the brain compared with the PLGA-PEG nanoparticles [50]

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