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Understanding these overlapping pathways helps explain why multiple peptide approaches may benefit MS through convergent mechanisms
10.1083/jcb.201701136 J
The 2013 Leggett paper used a GHRH-receptor-targeted botulinum-neurotoxin construct to further characterise pulsatile-secretion mechanisms (PMID 23825127)
282 Experimentally, this is evidenced by rapid feedback reactivation and state switching
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