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This included heart attack and stroke, by 20% in adults with obesity or overweight who already had cardiovascular disease, even without diabetes (Reference)

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For example, in the SELECT trial (17,600 patients with cardiovascular disease and obesity but without T2D), weekly subcutaneous Semaglutide (2.4 mg) reduced the risk of major adverse cardiovascular events (MACE heart attack, stroke, or cardiovascular death) by 20% compared to placebo (HR 0.80

Despite this progress, only 14% of patients remain on Wegovy after three years (Figure 3)

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