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doi: 10.2337/diab.42.5.658 95 ReedJBainSKanamarlapudiV
Baseline measurements were taken after an initial 5 min incubation with coelenterazine-h or NanoGlo-containing HBSS, after which cells were treated with either a vehicle (PBS) or the respective ligands
Both work by mimicking natural hormones in the body that help regulate blood sugar, appetite, and digestion
In another study, deoxyschizandrin-loaded liposomes increased the effect of deoxyschizandrin on adipocytes to reduce their differentiation through effective hepatic targeting, suggesting potential effects on alleviating lipid-associated diseases and nonalcoholic fatty liver disease (NAFLD) [134]
Microdosing starts at a significantly lower dose and increases more slowly, which substantially reduces the side effects that made previous attempts difficult
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