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Glutamate dehydrogenase hyperinsulinism (GDH-HI) is induced by mutations in the glutamate dehydrogenase 1 (GLUD1) gene, which through several pathways lead to augmentation of insulin release that is independent of extracellular glucose concentration

As a result, high pressure in the portal system develops

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De Duve, C., De Reuck, A

We hypothesized that GSH and GABA concentrations would be significantly lower in autism compared to TDC in all four brain regions

Glutathione is an antioxidant made up of three types of amino acids: glycine, cysteine, and glutamic acid