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GLP-1 medications include semaglutide, dulaglutide, and liraglutide, used for type 2 diabetes and weight management Common gastrointestinal effects (nausea, vomiting, diarrhoea) can lead to fluid loss and electrolyte depletion affecting muscle function Maintaining adequate hydration (1.52 litres daily) and dietary electrolyte intake may help prevent cramping Concurrent medications such as diuretics, SGLT2 inhibitors, and statins may contribute to muscle-related symptoms Persistent, severe, or frequent cramps warrant medical review to assess electrolytes, renal function, and exclude other causes Table of Contents What Are GLP-1 Medications and How Do They Work

These interventions have strong evidence, predictable outcomes, and clear safety profiles for knee patients

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Therapeutic effects were tested in an immunocompetent hydrodynamic HCC model with hepatocyte-specific Hkdc1 deletion and were analyzed a postoperative cohort (n=40) treated with lenvatinib+PD-1

Scand.J Clin Lab Invest 1985;45(2):179-184