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The native peptide GLP-1-G 2 ( 1 ) showed a decreased of blood glucose concentration after 30 min, proving its efficacy in vivo, although for a short time as a rapid raise to the initial concentration level is observed after 1 h
doi: 10.1142/S0192415X13500535 163 LiuL.WuJ.KennedyD
However, when combined with insulin or sulfonylureas, the risk increases significantly, and dose adjustments of these medications may be necessary
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La concentracin de carnitina necesaria para que la enzima carnitina aciltrasnfersa 1 (ver Figura 3) alcance su velocidad media de accin es de~ 400 a ~ 700 M, bastante por debajo de las concentraciones musculares normales (~ 4000 mol) y por lo tanto, en sujetos que no tengan una deficiencia de carnitina muscular el contenido normal de carnitina es suficiente para saturar al mximo la velocidad de transporte de los cidos grasos hacia la mitocondria (Brass 2004)
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