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doi:10.1001/jama.2024.10816 Fredrick TW, Camilleri M, Acosta A

These agents activate the cAMP-PKA signaling cascade in pancreatic -cells 6 , resulting in glucose-dependent insulin secretion, suppression of pancreatic -cell glucagon release, and modulation of gastrointestinal motility through delayed gastric emptying 7

GLP-1 agonists work by mimicking a natural hormone in your body that regulates appetite and food intake, often leading to reduced hunger

Part of it is due to the rapid weight loss and part of it is possibly a lack of proper nutrition in patients taking these medications, says John Diaz, MD, a plastic surgeon in Beverly Hills, CA

It can also help protect the skin from environmental stressors like UV rays and pollution