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DISCUSSION This manuscript reports that 18 h following AOM injection the BBB is significantly disrupted, as measured by Evans blue dye extravasation

Similarly, the current American Urological Association and American Society for Reproductive Medicine guidelines question the benefits of AOXs in treating male infertility, and indicate lack of data to recommend the use of specific agents for this purpose (Moderate Recommendation

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The Charlson Comorbidity Index (CCI, numeric variable) was calculated based on other comorbidities

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