However, gastrointestinal side effects, including diarrhea, constipation, and abdominal discomfort, have been reported in approximately 35% of patients, especially during initial usage
Evaluation of L-Carnitine Potential in Improvement of Male Fertility. Journal of Reproduction & Infertility , vol
Third, the optimal positioning and sequencing of GLP-1-based therapies relative to resmetirom and other emerging MASH agents (e.g., lanifibranor, pegozafermin, semaglutide combination regimens) requires dedicated combination trials, of which preliminary data from the MAESTRO-NASH secondary analysis are encouraging
Additional factors that may contribute to development of PI-IBS include alterations in intestinal flora, bile malabsorption, and altered levels of immune responders that influence serotonin levels
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