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Depletion of AP2XII-2 results in delayed S-phase progression, slowed parasite replication, and disruption of complex-mediated transcriptional repression, thereby permitting the expression of merozoite-specific transcription factor AP2X-10 and the oocyst wall-associated gene AAH1 in tachyzoites 14,15

At 2.5 mg/mL, each 10-unit mark is 0.25 mg, and the full 100-unit syringe covers 2.5 mg

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This upregulates MITF and Tyrosinase, driving the synthesis of eumelanin (photoprotective brown pigment) over pheomelanin

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