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After verifying oxidizing influences on Mia40 in vivo , we next wanted to test which reducing pathways act on Mia40 or more specifically whether the redox state of Mia40 is susceptible to changes in E GSH (Figure 8A)
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2023;8(1): e10367
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Figure 5A,B confirm a stable photoluminescence of PLGA nanoparticles encapsulating DDA-GSH-AuNCs in PBS or DMEM (Dulbeccos Modified Eagle Medium) contains 10% FBS (fetal bovine serum) for 24 hours with comparable photoluminescence stability in water as a control
3.2.2 MDA and tGSH assay results in paw tissue subjected to scalpel incision As shown in Figure 3, compared to the HC group, it was observed that tissue MDA levels increased and tGSH levels decreased after claw tissue was cut ( p 0.999
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