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Patients on metformin at a dose of at least 1,500 mg per day were randomized after completing a 2-week, single-blind, placebo lead-in period
Statements Acknowledgments Partial financial support received from Portuguese Foundation for Science and Technology (FCT) through post-doctoral research grants to NAA (SFRH/BPD/64690/2009
People with a diabetes diagnosis are excluded, because their GLP-1 medications should already be addressed under existing treatment guidelines and coverage
Allergic reactions are immune-mediated, can worsen with each exposure, and may spread beyond the application area
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