The available data is one short-duration clinical trial in surgical patients (which found it well tolerated) and early pharmacokinetic work in healthy volunteers that did not flag acute harms
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The use of these drugs has become common
In the STEP 1 trial, 44% of participants experienced nausea at the standard 2.4 mg dose, making it the most commonly reported complaint
Retatrutide and Type 2 Diabetes Research Retatrutide has been studied in people with type 2 diabetes because its receptor targets are directly relevant to glycemic control, insulin secretion, body weight, and metabolic health [5], [8]
Some people find arnica cream helps with bruising, and many use ice packs to manage swelling