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Obesity and health Adipose tissue is not an inert storage for lipids
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Although all three agents were prescribed within the same center, temporal changes in clinical experience, drug availability, and physician preference may have influenced treatment selection
Events such as the accumulation of visceral adipose tissue, increased plasma concentrations of free fatty acids, tissue hypoxia, and sympathetic hyperactivity in individuals with MetS may contribute to the activation of the innate immune response, which compromises cerebral microcirculation and the neurovascular unit, leading to the onset or progression of neurodegenerative diseases
There may be a role for microdosing in certain scenarios, such as when side effects are not manageable or intolerable for patients, even at the lowest introductory dose
Tip: Aim for at least 2535g of fiber daily, with an emphasis on fermentable fibers
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