new glp-1 weight loss The U.S. Food and Drug Administration approved Eli Lilly's pill, the company said, a major milestone for the Indianapolis-based drugmaker and one that will test the market for weight-loss medications What Is GLP-1 and Why

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117 Additionally, MAPK pathway hyperactivation, driven by NF1 loss, induces ligand-independent ER activation through persistent RAS signaling, contributing to endocrine resistance

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Whether GLP-1based therapies eventually fit into healthy-aging strategies will depend on larger studies establishing how durable the effects are, optimal dosing and duration, and whether benefits are enhanced when combined with diet, exercise and sleep, the researcher noted