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Amy Yasko, the most well tolerated active form of B12 for folks seems to be hydroxy B12. Every single one of the genetic combinations she lists below should be able to tolerate B12 in the form of hydroxy B12 (and this is why our methylation protocol suggests hydroxy B12 as the B12 form to begin with)
DSIP extends delta-wave time
Is high-dose vitamin C safe
The Discovery of the Microsomal Ethanol Oxidizing System and its Physiologic and Pathologic Role
The fluid will slowly drip into your vein over 30-60 minutes, depending on the specific formula and volume
Austin Journal of Pharmacology and Therapeutics
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