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Taken together, our results indicate that GIPR in the AP underlie the weight loss effects of GIPR agonism, whereas GIPR in the hypothalamus underlie the additional weight loss effects of adding GIPR antagonism to GLP-1R or amylin receptor agonism
2024, Nov;416(28):631731
Retatrutide is a peptide-based weight loss medication for type 2 diabetes and obesity
PMID 11118286
Educational information only
Concurrently, it alleviates hypoxia and depletes glutathione to amplify oxidative stress
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