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2021 Apr 13;325(14):1414

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Efficacy: Patients undergoing bariatric surgery often achieve a loss of 25% to 35% of their total body weight, with long-term maintenance being more common than with medication or diet alone

Activation of NRF2 by epiberberine improves oxidative stress and insulin resistance in T2DM mice and IR-HepG2 cells in an AMPK dependent manner