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RECONSTITUTION GUIDE To reconstitute GHK-Cu lyophilized powder: Allow vial to equilibrate to room temperature before opening Add sterile water or buffer slowly along the vial wall Recommended concentration: 15 mg/mL depending on application Gently swirl until fully dissolved (avoid shaking) Aliquot into sterile containers to minimize degradation Maintain sterile handling conditions throughout

6A) and prevented the increase of HIF1a and Tbr2 colocalization in INPs (Fig