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Semaglutide retains 94% amino acid homology with native GLP-1, allowing it to retain GLP-1 signaling functionality but with a half-life of about 1 week

Our bodies are made of proteins

The difference in efficacy between these two doses is modest, but the difference in side effects can be meaningful for some individuals

Individuals with a personal or family history of medullary thyroid carcinoma or MEN2 should discuss risks with their clinician before enrolment

The medication works as a glucagon-like peptide-1 (GLP-1) receptor agonist, which slows gastric emptying and reduces appetite

Both supplements are generally well-tolerated for long-term use at recommended doses, though they should be taken under medical supervision