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While the treatment with Ru(II)-OH or NP2 slightly elevated the ROS levels inside the hypoxic cancer cells, the treatment with NP4 showed a strong enhancement of ROS

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As a result, the UK government is advising patients and their doctors to pay close attention to the differences in formulas and how this may affect dosing decisions

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[1] Este frmaco no est indicado para diabetes tipo 1 ni ha sido aprobado para uso peditrico

doi:10.1152/physrev.1983.63.4.1420